The Profs placed four players in double figures led by Kate Herlihy with 16 points while nine of Holt's 10 points came from three made three-pointers. Jess McLaughlin also contributed 11 points and Nicole Mallard added 10 points as she connected on 4-of-5 from the field.
Samiyah Horton had a game-high 21 points for the Scarlet Raiders.
Rutgers-Newark (2-22; 1-16) started off the first quarter on a 9-0 run thanks to seven points from Horton. Mallard scored the first points of the game for Rowan off a layup, spurring a 16-2 run to close out the first quarter as Holt contributed two made three-pointers.
Rowan maintained a lead in the second quarter, with a Holt free throw giving the Profs a 24-17 lead, the largest of the quarter. Sabrina Araujo contributed three points during the quarter.
Rowan ended the first half up, 24-21, before taking control in the third quarter. A Herlihy jumper capped off a 14-5 run to start the quarter before the Profs finished the third up 48-33 as the junior scored eight points in the period.
Rowan went up by as many as 18 points in the fourth quarter after a Herlihy layup, maintaining a double-digit lead throughout the final frame. McLaughlin also contributed five points during the fourth.